Who is favored to win March Madness? Full tournament odds originally appeared on NBC Sports Chicago

The chances of filling out a perfect NCAA Tournament bracket is an impossible task, but there are other ways for college basketball fans to beat the odds in March.

Between 67 games and tournament futures, March Madness is a marquee event for betting. The seeding makes it easy to find the favorites, but as the 2023 edition has already shown, the tourney is famously home to Cinderella teams with a history of shaking things up.

Before the Sweet 16 tips off on Thursday, here is a look at the favorites for the NCAA Tournament and each region.

Who is favored to win March Madness 2023?

It came as no surprise that the four No. 1 seeds opened with the best odds to win it all, but the No. 1 overall seed was not originally listed as the overall favorite. Following the first two rounds, that has now changed.

Alabama leads the pack with +275 odds, according to our partner, PointsBet. The Crimson Tide rolled past No. 16 Texas A&M-CC and No. 8 Maryland in its first two tournament games after earning the top spot in the entire bracket. Next up for the team is a Sweet 16 tilt against No. 5 San Diego State on Friday.

Next on board is the only other remaining No. 1 seed, Houston, at +350. The Cougars took care of business against No. 16 Northern Kentucky and No. 9 Auburn last weekend and will face No. 5 Miami in the Sweet 16 on Friday.

Which team has the lowest odds to win March Madness 2023?

If you’re searching for a true Cinderella, look no further than Princeton.

The No. 15-seeded Tigers have pulled off two of the biggest upsets in this year’s tournament, first shocking No. 2 Arizona before beating No. 7 Missouri by 15 points.

Oddsmakers don’t love Princeton’s chances of winning four more games in March Madness, though. The team has +15000 odds to become champions.

Full March Madness 2023 odds

From Alabama on down, here are the full national title odds for the 16 teams left in March Madness:

• Alabama: +275
• Houston: +350
• Texas: +800
• UCLA: +800
• UConn: +800
• Creighton: +900
• Tennessee: +1000
• Gonzaga: +1000
• Kansas State: +2200
• Michigan State: +2500
• Xavier: +3000
• Arkansas: +3000
• Miami: +4000
• San Diego State: +4000
• Florida Atlantic: +5000
• Princeton: +15000

South Region odds

Alabama also has the shortest odds of reaching the Final Four out of the 16 teams remaining. The clear-cut favorite in the South Region, the Crimson Tide have an easy path that includes a No. 5 seed, a No. 6 seed and a No. 15 seed. 

• Alabama: -150
• Creighton: +200
• San Diego State: +550
• Princeton: +2500

Midwest Region odds

It’s Houston versus the field in the Midwest. The Cougars are given minus odds to reach the Final Four with Texas, Xavier and Miami in the rearview. 

• Houston: -110
• Texas: +210
• Xavier: +700
• Miami: +800

West Region odds

The West is far and away the most wide open region in oddsmakers’ eyes. UCLA and UConn share the same title odds, and they, along with Gonzaga, are effectively seen as co-favorites to make it out of the region.

• UCLA: +200
• UConn: +200
• Gonzaga: +250
• Arkansas: +550

East Region odds

While Kansas State is the lowest seed remaining in the East, Tennessee is listed as the favorite to win the region at Madison Square Garden this weekend.

• Tennessee: +125
• Michigan State: +300
• Kansas State: +350
• Florida Atlantic: +450

Editor's note: All odds are provided by our partner, PointsBet. PointsBet is our Official Sports Betting Partner and we may receive compensation if you place a bet on PointsBet for the first time after clicking our links.